Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | NDUFS8 | O00217 | 4/20 | 0.69 |
| ▸ | COXFA4 | O00483 | 4/20 | 0.69 |
| ▸ | NDUFAB1 | O14561 | 4/20 | 0.69 |
| ▸ | NDUFA1 | O15239 | 4/20 | 0.69 |
| ▸ | NDUFS4 | O43181 | 4/20 | 0.69 |
| ▸ | NDUFB5 | O43674 | 4/20 | 0.69 |
| ▸ | NDUFB3 | O43676 | 4/20 | 0.69 |
| ▸ | NDUFC1 | O43677 | 4/20 | 0.69 |
| ▸ | NDUFA2 | O43678 | 4/20 | 0.69 |
| ▸ | NDUFS5 | O43920 | 4/20 | 0.69 |
| ▸ | NDUFS7 | O75251 | 4/20 | 0.69 |
| ▸ | NDUFS2 | O75306 | 4/20 | 0.69 |
| ▸ | NDUFS6 | O75380 | 4/20 | 0.69 |
| ▸ | NDUFB1 | O75438 | 4/20 | 0.69 |
| ▸ | NDUFS3 | O75489 | 4/20 | 0.69 |
| ▸ | NDUFB6 | O95139 | 4/20 | 0.69 |
| ▸ | NDUFA3 | O95167 | 4/20 | 0.69 |
| ▸ | NDUFB4 | O95168 | 4/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457190 | 1.00 | ALOX15 (0.71) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| SCHEMBL11456503 | 0.99 | ALOX15 (0.71) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| SCHEMBL11456504 | 0.99 | ALOX15 (0.71) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| SCHEMBL18292786 | 0.86 | MAOB (0.80) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| SCHEMBL17701101 | 0.85 | MAOB (0.81) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| SCHEMBL17701103 | 0.85 | MAOB (0.81) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| Umbelliprenin SCHEMBL26641528 | 0.83 | ALOX15 (1.00) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| Umbelliprenin SCHEMBL18265478 | 0.83 | ALOX15 (1.00) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| Umbelliprenin SCHEMBL28133292 | 0.83 | ALOX15 (1.00) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 | |
| SCHEMBL18284618 | 0.83 | MAOB (0.81) | ALOX15TDP1NDUFS8COXFA4NDUFAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229467-A | Alkoxy benzofuran carboxylic acids and salts and esters thereof as hypolipidemic agents | RICHARDSON-MERRELL INC. (US) | 1980-10-21 | — | — | US | disclosed |