Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.66 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.66 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457232 | 1.00 | TDP1 (0.68) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11217715 | 0.93 | TDP1 (0.58) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11217610 | 0.93 | TDP1 (0.58) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11217710 | 0.93 | TDP1 (0.58) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11217615 | 0.93 | TDP1 (0.58) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL10991893 | 0.91 | TDP1 (0.70) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL10991889 | 0.91 | TDP1 (0.70) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11189704 | 0.90 | TDP1 (0.68) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11189706 | 0.90 | TDP1 (0.68) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11222186 | 0.87 | CA5A (0.55) | TDP1MAPTNR1I2SLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241057-A | Antibiotic compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-12-23 | — | — | US | disclosed |
| US-4161527-A | 7-B-(2-(2-IMINO-4-THIAZOLIN-4-YL)ACETAMIDO)-3-(1-(2-(N,N -DIMETHYLAMINO)ETHYL)-1-H-TETRAZOL-5-UL)THIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACID DIHYDROCHLORIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-07-17 | — | — | US | disclosed |
| US-4146710-A | ANTIBIOTIC, STORAGE, STABILITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-27 | — | — | US | disclosed |