Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11458500 | 0.99 | KDM4E (0.53) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL11448859 | 0.88 | ADRB2 (0.69) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL11448280 | 0.86 | ADRB2 (0.48) | ADRB2ADRB1KDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL11466527 | 0.85 | KDM4E (0.48) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL11455672 | 0.84 | ADRB2 (0.48) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL11459610 | 0.82 | ADRB2 (0.46) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL11459611 | 0.82 | ADRB2 (0.48) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL11456168 | 0.82 | ADRB2 (0.76) | ADRB2ADRB1KDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL11466712 | 0.81 | KDM4E (0.48) | ADRB2ADRB1KDM4EMEN1LMNA | |
| SCHEMBL11457889 | 0.80 | ADRB2 (0.43) | ADRB2ADRB1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223137-A | DILATION, HYPOTENSIVES, ANTIHISTAMINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-09-16 | — | — | US | claimed |