⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11602322 | 0.93 | CA1 (0.52) | — | |
| SCHEMBL1145060 | 0.92 | CA2 (0.56) | — | |
| SCHEMBL1012552 | 0.83 | — | — | |
| SCHEMBL10584337 | 0.80 | CA1 (0.67) | — | |
| SCHEMBL10532539 | 0.80 | CA1 (0.67) | — | |
| SCHEMBL12856657 | 0.78 | CA1 (0.55) | — | |
| SCHEMBL5147794 | 0.76 | — | — | |
| SCHEMBL3014275 | 0.75 | CA2 (0.44) | — | |
| SCHEMBL41856 | 0.74 | — | — | |
| SCHEMBL1447226 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036384-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
| US-8293256-B2 | Sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2012-10-23 | — | — | US | disclosed |
| US-8293256-B2 | Sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2012-10-23 | — | — | US | disclosed |
| US-20110044918-A1 | Novel sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2011-02-24 | — | — | US | disclosed |
| US-20110044918-A1 | Novel sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2011-02-24 | — | — | US | disclosed |
| US-7887824-B2 | such as N,N'-bis(2-hydroxyethyl)sulfamide; improved elasticity on stratum corneum | L'OREAL (FR) | 2011-02-15 | — | — | US | disclosed |
| US-7887824-B2 | such as N,N'-bis(2-hydroxyethyl)sulfamide; improved elasticity on stratum corneum | L'OREAL (FR) | 2011-02-15 | — | — | US | disclosed |
| EP-1669060-B9 | New sulfamide derivatives and their cosmetic use | OREAL (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1669060-B1 | New sulfamide derivatives and their cosmetic use | OREAL (FR) | 2008-05-07 | — | — | EP | disclosed |
| US-20060134151-A1 | Novel sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2006-06-22 | — | — | US | disclosed |