Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.75 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.75 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455586 | 0.96 | CHRNB4 (0.69) | CHRNB4CHRNA3CHRNB2CHRNA4CNR2 | |
| SCHEMBL3830309 | 0.86 | CHRNB4 (1.00) | CHRNB4CHRNA3 | |
| SCHEMBL14578215 | 0.84 | CHRNB4 (0.52) | CHRNB4CHRNA3SSTR2 | |
| SCHEMBL11466396 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11455927 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL3973615 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11458473 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11450540 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL7955171 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11455784 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |