Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578215 | 0.84 | CHRNB4 (0.52) | CHRNB4CHRNA3LTA4HCHEK2 | |
| SCHEMBL11455982 | 0.84 | CHRNB4 (0.50) | CHRNB4CHRNA3LTA4HCHEK2 | |
| SCHEMBL11450540 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11455927 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11455784 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11466396 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL11458259 | 0.83 | CHRNB4 (0.75) | CHRNB4CHRNA3 | |
| SCHEMBL11458473 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3 | |
| SCHEMBL7955171 | 0.83 | CHRNB4 (0.52) | CHRNB4CHRNA3LTA4H | |
| SCHEMBL11712033 | 0.83 | CHRNB4 (0.47) | CHRNB4CHRNA3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049028-A1 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS | TARGEGEN INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2007056023-A2 | THIAZOLE INHIBITORS TARGETING RESISTANT KINASE MUTATIONS | TARGEGEN, INC. (US) | 2007-05-18 | — | — | WO | disclosed |