Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 3/20 | 0.31 |
| ▸ | HTR5A | P47898 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11466742 | 0.98 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11457005 | 0.90 | MAPT (0.41) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL29414938 | 0.78 | MAPT (0.38) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL30122588 | 0.71 | MAPT (0.41) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL29292325 | 0.71 | PDE3B (0.38) | KMT2AKDM4EACHEPDE3BPDE3A | |
| SCHEMBL11541662 | 0.71 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL21154239 | 0.68 | ACHE (0.38) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11472482 | 0.66 | AHR (0.38) | NPC1RAB9ASMN1; SMN2KMT2AHTR2B | |
| SCHEMBL11457079 | 0.66 | AHR (0.38) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29293278 | 0.65 | PDE3B (0.41) | MAPTKMT2AKDM4EMEN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164407-A | Benzoxazine herbicides | SANDOZ, INC. (US) | 1979-08-14 | — | — | US | claimed |
| US-4214889-A | Benzoxazine herbicides | SANDOZ, INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4164407-A | Benzoxazine herbicides | SANDOZ, INC. (US) | 1979-08-14 | — | — | US | disclosed |