Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11393456 | 0.83 | ACLY (0.32) | — | |
| SCHEMBL11223444 | 0.81 | — | — | |
| SCHEMBL11386665 | 0.81 | — | — | |
| SCHEMBL11223448 | 0.81 | — | — | |
| SCHEMBL7049572 | 0.76 | — | — | |
| SCHEMBL777370 | 0.74 | — | — | |
| SCHEMBL11574622 | 0.74 | — | — | |
| SCHEMBL7049576 | 0.70 | — | — | |
| SCHEMBL777956 | 0.67 | — | — | |
| SCHEMBL7054475 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4236001-A | 7β-Acyloxy-3-heterocyclicthiomethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4218564-A | 7β-Hydroxy-3-heterocyclicthio-methyl cephalosporin intermediates | SMITHKLINE CORPORATION (US) | 1980-08-19 | — | — | US | disclosed |
| US-4158733-A | 7β-Acyloxy-3-acetoxymethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1979-06-19 | — | — | US | disclosed |
| US-4131734-A | 7β-Acyloxy-3-heterocyclicthiomethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
| US-4020057-A | 7β-Acyloxy cephalosporins | SMITHKLINE CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |