Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483076 | 0.90 | ALDH1A1 (0.53) | ADRB3ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL11465953 | 0.90 | ALDH1A1 (0.50) | ADRB3ADRB1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11451326 | 0.90 | ALDH1A1 (0.53) | ADRB3ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL11110907 | 0.90 | ALDH1A1 (0.50) | ADRB3ADRB1ALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11472436 | 0.88 | ALDH1A1 (0.49) | ADRB3ADRB1ALDH1A1KDM4EL3MBTL1 | |
| Bromide SCHEMBL11475191 | 0.88 | ALDH1A1 (0.49) | ADRB3ADRB1ALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11477462 | 0.88 | ALDH1A1 (0.55) | ADRB3ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL11459286 | 0.87 | KDM4E (0.59) | ADRB3ADRB1ALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11465962 | 0.87 | KDM4E (0.61) | ADRB3ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11463488 | 0.82 | KDM4E (0.51) | ADRB3ALDH1A1KDM4EL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006735-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | disclosed |