Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.58 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532908 | 0.90 | NR1I2 (0.74) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11281925 | 0.90 | NR1I2 (0.74) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11039470 | 0.90 | NR1I2 (0.74) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11281918 | 0.90 | NR1I2 (0.74) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL8982879 | 0.90 | NR1I2 (0.74) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11039460 | 0.90 | NR1I2 (0.74) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL8982871 | 0.90 | NR1I2 (0.74) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL6703100 | 0.89 | CA5A (0.48) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL9344856 | 0.89 | MAPT (0.64) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL9684935 | 0.89 | MAPT (0.64) | TDP1MAPTNR1I2SLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201779-A | 7[(2-Amino-thiazol-4-yl)glyoxylamido]-cephem derivatives and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| EP-0005785-A1 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-12-12 | — | — | EP | disclosed |