Trolamine

Trolamine

SCHEMBL1146

OCCN(CCO)CCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
KDM4E B2RXH2 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALOX15 P16050 1/20 0.41
HPGD P15428 2/20 0.38
MAPK1 P28482 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL15845959 1.00 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL434089 1.00 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL4748243 1.00 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
SCHEMBL2157617 0.95 MAPT (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL565435 0.95 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
SCHEMBL23528233 0.95 MAPT (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL5934922 0.95 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL5862137 0.95 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL9716114 0.95 TSHR (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD
SCHEMBL9785641 0.95 MAPT (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 688279 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410494-B1 None US claimed
CN-118325556-A High-low temperature-resistant polyurethane adhesive and preparation method and application thereof 华南理工大学 2024-07-12 CN claimed
EP-4397631-A2 METHODS TO REDUCE N-HETEROCYCLES BL TECHNOLOGIES, Inc. (US) 2024-07-10 EP claimed
CN-115252449-B Azelaic acid aqueous solution, preparation method thereof and cosmetic composition 上海臻臣化妆品有限公司 2024-07-05 CN claimed
CN-115969777-B Tetrahydropalmatine-bletilla polysaccharide latex and preparation method thereof 陕西中医药大学 2024-07-05 CN claimed
CN-118291177-A Rocket jet fuel production method 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-114752035-B High-solid-content aqueous polyurethane dispersion and preparation method and application thereof 浙江大学衢州研究院 2024-07-05 CN claimed
CN-118284643-A Coating composition 湛新奥地利有限公司 2024-07-02 CN claimed
CN-114533589-B Low-viscosity emulsion and preparation method and application thereof 上海自然堂集团有限公司 2024-07-02 CN claimed
CN-118273127-A Organosilicon emulsion and preparation method thereof 江苏四新科技应用研究所股份有限公司 2024-07-02 CN claimed
US-3932334-A LOW POLLUTANT PHENOL-FORMALDEHYDE RESINS, LOW MONOMETHYLOLPHENOL - HIGH O,P-DIMETHYLOLPHENOL CONTENT DEUZEMAN HENDRIK H J 1976-01-13 US claimed
US-3932126-A Dyeing assistant composition containing organic amines and carboxylic acids for coloring polyester material with acid dyes MARTIN PROCESSING CO., INC. (US) 1976-01-13 US claimed
US-3932439-A N-substituted cycloserine compounds, salts thereof, and processes for preparing them MERCK & CO., INC. (US) 1976-01-13 US claimed
US-3931053-A NICKEL, ALUMINUM, MAGNESIUM, CALCIUM, BARIUM OXIDES KAZAKOV EVGENY VASILIEVICH 1976-01-06 US claimed
US-3931262-A Hydrophilic and difficultly volatile biocidal triorganotin compounds CIBA-GEIGY CORPORATION (US) 1976-01-06 US claimed
US-3931079-A SHOE, ENDCAPPED POLYOXYETHYLENE GLYCOL, DIMETHYL POLYSILOXANE, EMULSIFIER, MORPHOLINE, TRIETHANOLAMINE, DYE, CARBOXY VINYL POLYMER AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US claimed
US-3931122-A METHOD FOR PRODUCING HIGH MOLECULAR WEIGHT POLYACRYLAMIDE TYPE RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-01-06 US claimed
US-3931208-A Process for the production of thiazolines-(3) DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-01-06 US claimed
US-3930813-A PROCESS FOR PRODUCING NITROGEN DIOXIDE-FREE OXYGEN-ENRICHED GAS GENERAL ELECTRIC COMPANY (US) 1976-01-06 US claimed
US-3930834-A ALGAECIDAL COMPOSITION APPLIED BIOCHEMISTS, INC. (US) 1976-01-06 US claimed