Trolamine

Trolamine

SCHEMBL434089

OCCN(CCO)CCO.OCCN(CCO)CCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
KDM4E B2RXH2 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALOX15 P16050 1/20 0.41
HPGD P15428 2/20 0.38
MAPK1 P28482 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL15845959 1.00 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL1146 1.00 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL4748243 1.00 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
SCHEMBL2157617 0.95 MAPT (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL565435 0.95 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
SCHEMBL23528233 0.95 MAPT (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL5934922 0.95 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL5862137 0.95 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL9716114 0.95 TSHR (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD
SCHEMBL9785641 0.95 MAPT (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111500266-A Completion fluid composition and application thereof 中国石油化工股份有限公司 2020-08-07 CN claimed
CN-1183271-A Collagen E milk and preparing method thereof FAMA MEDICAL CONSULTATION CO L (CN) 1998-06-03 CN claimed
US-20230295595-A1 SUBTILASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2023-09-21 US disclosed
EP-3878960-A1 SUBTILASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2021-09-15 EP disclosed
EP-3739029-A1 SUBTILASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2020-11-18 EP disclosed
EP-3234122-B1 SUBTILASE VARIANTS NOVOZYMES AS (DK) 2020-10-14 EP disclosed
CN-111500266-A Completion fluid composition and application thereof 中国石油化工股份有限公司 2020-08-07 CN disclosed
US-10626388-B2 Subtilase variants and polynucleotides encoding same NOVOZYMES A/S (DK) 2020-04-21 US disclosed
EP-3608403-A2 DETERGENT COMPOSITION COMPRISING SUBTILASE VARIANTS Henkel AG & Co. KGaA (DE) 2020-02-12 EP disclosed
EP-3399031-B1 DETERGENT COMPOSITION COMPRISING SUBTILASE VARIANTS HENKEL AG & CO KGAA (DE) 2019-10-30 EP disclosed
CN-110225954-A Water-base drilling fluid lubricant 沙特阿拉伯石油公司 2019-09-10 CN disclosed
US-6036963-A COSMETICS FOR SKIN WITH RETINOL, RETINOIC ACID, RETINAL, RETINYL ESTER AND MIXTURES WITH LACTONES AND VEHICLES CHESEBROUGH-PONDS'S USA CO., DIVISION OF CONOPCO, INC. (US) 2000-03-14 US disclosed
WO-2000006116-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR MANAGING SKIN CONDITIONS MURAD HOWARD (US) 2000-02-10 WO disclosed
WO-1999047110-A1 COSMETIC METHOD OF TREATING SKIN UNILEVER PLC (GB) 1999-09-23 WO disclosed
CN-1183271-A Collagen E milk and preparing method thereof FAMA MEDICAL CONSULTATION CO L (CN) 1998-06-03 CN disclosed
WO-1997010100-A1 WET WIPES WITH LOW VISCOSITY SILICONE EMULSION SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 1997-03-20 WO disclosed
WO-1989010114-A1 COMPOSITION FOR PROMOTING HAIR GROWTH IN ANDROGENETIC ALOPECIA AND METHOD THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 1989-11-02 WO disclosed
EP-0296205-A4 METHOD AND COMPOSITION FOR HAIR GROWTH IN COMMON PATTERN BALDNESS. UNIV BOSTON (US) 1989-03-14 EP disclosed
EP-0296205-A1 METHOD AND COMPOSITION FOR HAIR GROWTH IN COMMON PATTERN BALDNESS TRUSTEES OF BOSTON UNIVERSITY (US) 1988-12-28 EP disclosed
WO-1988004931-A1 METHOD AND COMPOSITION FOR HAIR GROWTH IN COMMON PATTERN BALDNESS TRUSTEES OF BOSTON UNIVERSITY (US) 1988-07-14 WO disclosed