⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867994 | 0.72 | CYP2A6 (0.33) | — | |
| SCHEMBL29521773 | 0.72 | CYP2A6 (0.33) | — | |
| SCHEMBL28017676 | 0.70 | L3MBTL1 (0.32) | — | |
| SCHEMBL4632918 | 0.65 | — | — | |
| SCHEMBL31318257 | 0.64 | SLC6A4 (0.43) | — | |
| SCHEMBL11731245 | 0.62 | — | — | |
| SCHEMBL7218149 | 0.61 | FFAR1 (0.55) | — | |
| SCHEMBL8307798 | 0.59 | — | — | |
| Formaldehyde SCHEMBL28680174 | 0.59 | CYP2A6 (0.62) | — | |
| SCHEMBL28199189 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575249-B2 | High heat-resistant polygermane compound with sulfur-containing organic group | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| US-20130059951-A1 | HIGH HEAT-RESISTANT POLYGERMANE COMPOUND WITH SULFUR-CONTAINING ORGANIC GROUP | TOHOKU UNIVERSITY (JP) | 2013-03-07 | — | — | US | disclosed |
| EP-2537852-A1 | POLYGERMANE COMPOUND WITH SULPHUR-CONTAINING ORGANIC GROUP DISPLAYING HIGH HEAT RESISTANCE | Nissan Chemical Industries, Ltd. (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-7888374-B2 | Inhibitors of c-jun N-terminal kinases | ABBOTT LABORATORIES (US) | 2011-02-15 | — | — | US | disclosed |
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | ABBVIE INC. | 2006-08-03 | — | — | US | disclosed |
| US-20050171132-A1 | Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists | XIN ZHILI (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |