Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.32 |
| ▸ | MAOB | P27338 | 8/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494429 | 0.81 | TSHR (0.39) | LMNAATMPDE2A | |
| SCHEMBL11212275 | 0.79 | NPC1 (0.44) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL11462243 | 0.79 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL3630819 | 0.77 | NPC1 (0.50) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL11946784 | 0.76 | NPC1 (0.42) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL11460883 | 0.75 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL17359700 | 0.73 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL10265206 | 0.73 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL11556361 | 0.73 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL14671240 | 0.73 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202894-A | AGRICULTURE | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |
| EP-0005541-A2 | Substituted piperidine, morpholine or piperidone derivatives, fungicides containing these compounds, process for their preparation and their use, and the use of these compounds as fungicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-11-28 | — | — | EP | disclosed |