Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706529 | 0.85 | NPC1 (0.44) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL3630819 | 0.83 | NPC1 (0.50) | NPC1RAB9AMAPTPTPN5LMNA | |
| SCHEMBL8364561 | 0.80 | NPC1 (0.41) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL14671240 | 0.79 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL10265206 | 0.79 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL17359700 | 0.79 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL779443 | 0.79 | NPC1 (0.58) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL13706559 | 0.79 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL18282984 | 0.78 | LMNA (0.50) | PTPN5LMNANOS3NOS1UGT2B7 | |
| SCHEMBL2644008 | 0.78 | LMNA (0.50) | PTPN5LMNANOS3NOS1UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150059-A | Dehydration of alpha-methylbenzyl alcohols over silica to form monovinylidene aromatic monomers | THE DOW CHEMICAL COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4049736-A | SILICA GEL CATALYST | THE DOW CHEMICAL COMPANY (US) | 1977-09-20 | — | — | US | disclosed |