Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146050 | 0.94 | EBP (0.70) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL4454622 | 0.94 | EBP (0.70) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL11927700 | 0.94 | EBP (0.70) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL4454620 | 0.94 | EBP (0.70) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL11927701 | 0.94 | EBP (0.70) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| Hydrochloric Acid SCHEMBL28017968 | 0.93 | EBP (0.68) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| Hydrochloric Acid SCHEMBL28469297 | 0.93 | EBP (0.68) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL11461196 | 0.89 | EBP (0.67) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL11462886 | 0.85 | SIGMAR1 (0.74) | EBPSIGMAR1ADORA3CHRM1DRD3 | |
| SCHEMBL9363925 | 0.84 | SIGMAR1 (0.77) | EBPSIGMAR1ADORA3CHRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202894-A | AGRICULTURE | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | claimed |
| US-4202894-A | AGRICULTURE | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |