Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462469 | 1.00 | HCAR3 (0.51) | HCAR3EPHX2MERTKLMNAPOLB | |
| SCHEMBL11480463 | 0.93 | EPHX2 (0.45) | HCAR3EPHX2MERTKSRD5A2LTA4H | |
| SCHEMBL11463386 | 0.93 | EPHX2 (0.45) | HCAR3EPHX2MERTKSRD5A2LTA4H | |
| SCHEMBL11460614 | 0.93 | EPHX2 (0.45) | HCAR3EPHX2MERTKSRD5A2LTA4H | |
| SCHEMBL11460615 | 0.93 | EPHX2 (0.45) | HCAR3EPHX2MERTKSRD5A2LTA4H | |
| SCHEMBL11460613 | 0.93 | EPHX2 (0.45) | HCAR3EPHX2MERTKSRD5A2LTA4H | |
| SCHEMBL11463388 | 0.93 | EPHX2 (0.45) | HCAR3EPHX2MERTKSRD5A2LTA4H | |
| SCHEMBL11478987 | 0.92 | HCAR3 (0.58) | HCAR3EPHX2MERTKLMNAPOLB | |
| SCHEMBL11461585 | 0.92 | HCAR3 (0.58) | HCAR3EPHX2MERTKLMNAPOLB | |
| SCHEMBL11465510 | 0.92 | HCAR3 (0.58) | HCAR3EPHX2MERTKLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4227014-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | claimed |