Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | MIF | P14174 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 3/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | GAPDH | P04406 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11825435 | 0.99 | NPC1 (0.61) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11823066 | 0.86 | MIF (0.64) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11836485 | 0.86 | MIF (0.64) | MIFMAOBSTSESR2 | |
| SCHEMBL11748471 | 0.86 | MIF (0.64) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11833595 | 0.83 | PGR (0.51) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11756710 | 0.82 | NPC1 (0.67) | NPC1MIFRAB9AMAOBKMT2A | |
| SCHEMBL8525223 | 0.81 | NPC1 (0.57) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11207121 | 0.81 | NPC1 (0.63) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL984946 | 0.80 | NPC1 (0.77) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11753022 | 0.79 | STS (0.58) | NPC1MIFRAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182861-A | OPTICAL BRIGHTENERS FOR POLYESTER, COTTON, POLYAMIDE AND POLYACRYLONITRILE FABRICS, POLYVINYL CHLORIDE FOILS | SANDOZ LTD. (CH) | 1980-01-08 | — | — | US | disclosed |
| US-4006158-A | Fluorescent 1,2,3-triazole derivatives of 3-phenylcoumarin | SANDOZ LTD. (CH) | 1977-02-01 | — | — | US | disclosed |
| US-3968119-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3965094-A | Process for the manufacture of 2-aryl-v-triazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-22 | — | — | US | disclosed |
| US-3957817-A | BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3947412-A | CYCLIZATION IN THE PRESENCE OF HEAVY METALS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | disclosed |