Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983839 | 0.79 | TDP1 (0.47) | NPC1RAB9APDE4APDE4BPDE4C | |
| SCHEMBL9375365 | 0.76 | CYP19A1 (0.48) | NPC1RAB9A | |
| SCHEMBL8538147 | 0.76 | CYP19A1 (0.48) | NPC1RAB9A | |
| SCHEMBL10946464 | 0.75 | ACACB (0.50) | NPC1RAB9APDE4APDE4BPDE4C | |
| SCHEMBL3718825 | 0.75 | HPGD (0.46) | KMO | |
| SCHEMBL981699 | 0.75 | TDP1 (0.46) | PDE4APDE4BPDE4CPDE4DTDP1 | |
| SCHEMBL2004375 | 0.74 | S1PR4 (0.51) | NPC1RAB9AS1PR4TDP1MRGPRX4 | |
| SCHEMBL745570 | 0.74 | MAPT (0.49) | NPC1RAB9AKMOMRGPRX4 | |
| SCHEMBL14812351 | 0.73 | POLB (0.54) | NPC1RAB9APDE4APDE4BPDE4C | |
| SCHEMBL8536866 | 0.73 | MAPT (0.51) | NPC1RAB9AS1PR4TDP1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208425-A | VIRICIDES | STERLING DRUG INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4153719-A | Aromatic diketones | STERLING DRUG INC. (US) | 1979-05-08 | — | — | US | disclosed |