Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375365 | 1.00 | CYP19A1 (0.48) | CYP19A1NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8542104 | 0.79 | MEN1 (0.46) | CYP19A1RAB9AMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9270397 | 0.79 | MEN1 (0.46) | CYP19A1RAB9AMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL9270401 | 0.79 | MEN1 (0.46) | CYP19A1RAB9AMEN1KMT2AMAPK1 | |
| SCHEMBL9261725 | 0.79 | MAPK1 (0.45) | CYP19A1RAB9AMEN1KMT2AMAPK1 | |
| SCHEMBL9261716 | 0.79 | MAPK1 (0.45) | CYP19A1RAB9AMEN1KMT2AMAPK1 | |
| SCHEMBL9285699 | 0.77 | KDM4E (0.70) | RAB9AMEN1KMT2AMAPK1TP53 | |
| SCHEMBL11464483 | 0.76 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL9267414 | 0.75 | MEN1 (0.72) | RAB9AMEN1KMT2AMAPK1TP53 | |
| SCHEMBL9260326 | 0.75 | MEN1 (0.72) | RAB9AMEN1KMT2AMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274867-B1 | Pharmaceutically active compounds | SCHERING CORP (US) | 1994-04-13 | — | — | EP | claimed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | claimed |
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| US-5459144-A | Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0274867-B1 | Pharmaceutically active compounds | SCHERING CORP (US) | 1994-04-13 | — | — | EP | disclosed |
| US-5272167-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4851423-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |