Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428385 | 0.84 | TP53 (0.58) | KMT2AELANETP53TSHRMEN1 | |
| SCHEMBL5610692 | 0.79 | KMT2A (0.61) | KMT2ADPP4KCNA5KCNH2MME | |
| SCHEMBL4630258 | 0.79 | KMT2A (0.60) | KMT2ADPP4KCNA5KCNH2MME | |
| SCHEMBL4428392 | 0.79 | TP53 (0.51) | KMT2AELANETP53TSHRCYP2D6 | |
| SCHEMBL27459066 | 0.79 | KMT2A (0.61) | KMT2ADPP4KCNA5KCNH2MME | |
| SCHEMBL28466587 | 0.77 | GABRA1 (0.47) | KMT2AELANETP53TSHRMEN1 | |
| Bicarbonate SCHEMBL27541289 | 0.76 | KMT2A (0.68) | KMT2ADPP4KCNA5KCNH2MME | |
| SCHEMBL7933543 | 0.76 | TSHR (0.42) | KMT2AKCNH2ELANETP53TSHR | |
| SCHEMBL5609724 | 0.76 | KMT2A (0.56) | KMT2ADPP4KCNA5KCNH2MME | |
| SCHEMBL27298513 | 0.76 | KMT2A (0.56) | KMT2ADPP4KCNA5KCNH2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202894-A | AGRICULTURE | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |