Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445818 | 0.88 | VEGFA (0.39) | MAPTAKR1C3AKR1C2PGRNR3C2 | |
| SCHEMBL11446152 | 0.86 | GRIA4 (0.46) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL11446226 | 0.84 | CYP2A6 (0.41) | AKR1C3AKR1C2 | |
| SCHEMBL11830296 | 0.83 | SCN9A (0.40) | AKR1C3AKR1C2AOC3 | |
| SCHEMBL11445854 | 0.77 | GRIA4 (0.44) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL11837141 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2GRM6KDM4EMAPT | |
| SCHEMBL11827580 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2GRM6KDM4EMAPT | |
| SCHEMBL11456667 | 0.76 | CYP2C19 (0.43) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 | |
| SCHEMBL11464739 | 0.76 | GRIA4 (0.42) | ALDH1A1MAPTNPSR1L3MBTL1 | |
| SCHEMBL11446336 | 0.75 | PPARG (0.44) | ALDH1A1MAPTHPGDNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191776-A | ANTITHROMBOTICS, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-3993683-A | ANTITHROMBOTIC, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-23 | — | — | US | disclosed |