Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455487 | 0.87 | MAPK1 (0.62) | KMT2AMEN1MAPTHPGDHTT | |
| SCHEMBL1974627 | 0.86 | MEN1 (0.58) | KMT2AMEN1MAPTRAB9AL3MBTL1 | |
| SCHEMBL680212 | 0.84 | L3MBTL1 (0.56) | KMT2AMEN1MAPTPOLBHPGD | |
| SCHEMBL11629180 | 0.84 | KMT2A (0.53) | KMT2AMEN1MAPTPOLBHPGD | |
| SCHEMBL11789135 | 0.83 | POLB (0.51) | KMT2AMEN1MAPTPOLBHPGD | |
| SCHEMBL1717101 | 0.77 | RECQL (0.55) | KMT2AMEN1MAPTHTTNPC1 | |
| SCHEMBL17335741 | 0.76 | HTT (0.59) | KMT2AMEN1MAPTHPGDHTT | |
| SCHEMBL23147387 | 0.76 | POLB (0.47) | KMT2AMEN1MAPTPOLBHPGD | |
| SCHEMBL23146961 | 0.75 | POLB (0.44) | KMT2AMEN1MAPTPOLBHPGD | |
| SCHEMBL1974506 | 0.75 | MEN1 (0.57) | KMT2AMEN1MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238220-A | PLANT GROWTH REGULATORS; SEEDICIDES | ROHM AND HAAS COMPANY (US) | 1980-12-09 | — | — | US | disclosed |