Terephthalic Acid

Terephthalic Acid

SCHEMBL11465633

O=C(O)c1ccc(C(=O)O)cc1.Oc1ccccc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.79
CA2 P00918 4/20 0.79
CA12 O43570 3/20 0.79
CA9 Q16790 3/20 0.79
CA3 P07451 2/20 0.79
CA4 P22748 2/20 0.79
CA14 Q9ULX7 2/20 0.79
CA6 P23280 2/20 0.79
TYR P14679 1/20 0.79
DRD1 P21728 1/20 0.79
CA5A P35218 1/20 0.79
CA7 P43166 1/20 0.79
CA5B Q9Y2D0 1/20 0.79
TSHR P16473 3/20 0.68
DAO P14920 1/20 0.68
NAPRT Q6XQN6 1/20 0.68
SRD5A2 P31213 3/20 0.68
TP53 P04637 1/20 0.67
CES2 O00748 2/20 0.64
CES1 P23141 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL787086 1.00 CA1 (0.79) CA1CA2CA12CA9CA3
Paraben SCHEMBL9796837 0.97 CA12 (0.84) CA1CA2CA12CA9CA3
Paraben SCHEMBL10457334 0.97 CA12 (0.84) CA1CA2CA12CA9CA3
Benzoic Acid SCHEMBL10630775 0.94 TSHR (0.78) CA1CA2CA12CA9CA3
Benzoic Acid SCHEMBL27622985 0.94 TSHR (0.78) CA1CA2CA12CA9CA3
Benzoic Acid SCHEMBL25410474 0.94 TSHR (0.78) CA1CA2CA12CA9CA3
Benzoic Acid SCHEMBL484290 0.94 TSHR (0.78) CA1CA2CA12CA9CA3
Benzoic Acid SCHEMBL28857724 0.94 TSHR (0.78) CA1CA2CA12CA9CA3
Phenol SCHEMBL9013973 0.93 EGFR (0.70) CA1CA2CA12CA9CA3
Paraben SCHEMBL3269042 0.93 CA12 (0.76) CA1CA2CA12CA9CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1280644-C Polarizing beam splitter 3M INNOVATIVE PROPERTIES CO (US) 2006-10-18 CN claimed
CN-1524190-A Polarizing beam splitter 3M 2004-08-25 CN claimed
CN-207924691-U Fingerprint recognition and touch-control sensing component, display module and terminal device 南昌欧菲光科技有限公司 2018-09-28 CN disclosed
CN-207924638-U Inductive component, display module and terminal device 南昌欧菲光科技有限公司 2018-09-28 CN disclosed
CN-108350285-A Conductive nano-particles dispersion primer composition and its preparation and application 沙特基础工业全球技术有限公司 2018-07-31 CN disclosed
CN-108350256-A High texture replication sheet compositions, methods of manufacture, and articles made therefrom 沙特基础工业全球技术有限公司 2018-07-31 CN disclosed
CN-1280644-C Polarizing beam splitter 3M INNOVATIVE PROPERTIES CO (US) 2006-10-18 CN disclosed
CN-1524190-A Polarizing beam splitter 3M 2004-08-25 CN disclosed
US-4189603-A CATALYTIC OXIDATION OF A P-DIALKULBENZENE IN PRESENCE OF A PHENOL AND ALIPHATIC CARBOXYLIC ACID SOLVENT MATSUYAMA PETROCHEMICALS INC. (JP) 1980-02-19 US disclosed