Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.79 |
| ▸ | CA2 | P00918 | 4/20 | 0.79 |
| ▸ | CA12 | O43570 | 3/20 | 0.79 |
| ▸ | CA9 | Q16790 | 3/20 | 0.79 |
| ▸ | CA3 | P07451 | 2/20 | 0.79 |
| ▸ | CA4 | P22748 | 2/20 | 0.79 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.79 |
| ▸ | CA6 | P23280 | 2/20 | 0.79 |
| ▸ | TYR | P14679 | 1/20 | 0.79 |
| ▸ | DRD1 | P21728 | 1/20 | 0.79 |
| ▸ | CA5A | P35218 | 1/20 | 0.79 |
| ▸ | CA7 | P43166 | 1/20 | 0.79 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | DAO | P14920 | 1/20 | 0.68 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11465633 | 1.00 | CA1 (0.79) | CA1CA2CA12CA9CA3 | |
| Paraben SCHEMBL9796837 | 0.97 | CA12 (0.84) | CA1CA2CA12CA9CA3 | |
| Paraben SCHEMBL10457334 | 0.97 | CA12 (0.84) | CA1CA2CA12CA9CA3 | |
| Benzoic Acid SCHEMBL10630775 | 0.94 | TSHR (0.78) | CA1CA2CA12CA9CA3 | |
| Benzoic Acid SCHEMBL27622985 | 0.94 | TSHR (0.78) | CA1CA2CA12CA9CA3 | |
| Benzoic Acid SCHEMBL25410474 | 0.94 | TSHR (0.78) | CA1CA2CA12CA9CA3 | |
| Benzoic Acid SCHEMBL484290 | 0.94 | TSHR (0.78) | CA1CA2CA12CA9CA3 | |
| Benzoic Acid SCHEMBL28857724 | 0.94 | TSHR (0.78) | CA1CA2CA12CA9CA3 | |
| Phenol SCHEMBL9013973 | 0.93 | EGFR (0.70) | CA1CA2CA12CA9CA3 | |
| Paraben SCHEMBL3269042 | 0.93 | CA12 (0.76) | CA1CA2CA12CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459714-B | Polyurethane grouting material, preparation method and application thereof | 广州隧华智慧交通科技有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-118773756-A | Winding mechanism for preparing polypropylene filaments and method for preparing filaments by using winding mechanism | 扬州市奕轩纤维有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118459714-A | Polyurethane grouting material, preparation method and application thereof | 广州隧华智慧交通科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| WO-2019175778-A1 | IMPROVED FLAME RETARDANT COMPOSITIONS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-09-19 | — | — | WO | claimed |
| WO-2017100397-A1 | ADDITIVE MANUFACTURING ARTICLES USEFUL IN AIRCRAFT | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-15 | — | — | WO | claimed |
| CN-101930189-B | Purified polyester resins for toner performance improvement | XEROX CORP | 2014-07-23 | — | — | CN | claimed |
| CN-101930189-A | Can improve the purified polyester resins of toner performance | XEROX CORP | 2010-12-29 | — | — | CN | claimed |
| WO-2007001938-A2 | MULTILAYER OPTICAL COMPENSATOR, DISPLAY, AND PROCESS | NITTO DENKO CORPORATION (JP) | 2007-01-04 | — | — | WO | claimed |
| US-4992323-A | Fatigue and heat resistant; aircraft, spacecraft | AKZO NV (NL) | 1991-02-12 | — | — | US | claimed |
| JP-62032464-A | — | — | None | — | — | JP | disclosed |
| US-12404437-B2 | Fiber reinforced flexible foams | L&P PROPERTY MANAGEMENT COMPANY (US) | 2025-09-02 | — | — | US | disclosed |
| CN-118459714-B | Polyurethane grouting material, preparation method and application thereof | 广州隧华智慧交通科技有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-118773756-A | Winding mechanism for preparing polypropylene filaments and method for preparing filaments by using winding mechanism | 扬州市奕轩纤维有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118459714-A | Polyurethane grouting material, preparation method and application thereof | 广州隧华智慧交通科技有限公司 | 2024-08-09 | — | — | CN | disclosed |
| US-20070166638-A1 | Method of manufacturing toner and toner | SHARP KABUSHIKI KAISHA (JP) | 2007-07-19 | — | — | US | disclosed |
| WO-2006071682-A2 | TRANSPARENT COMPOSITIONS, METHODS FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |
| US-20060142527-A1 | Transparent compositions, methods for the preparation thereof, and articles derived therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2006-06-29 | — | — | US | disclosed |
| JP-S6232464-A | ELECTROPHOTOGRAPHIC SENSITIVE BODY | CANON INC | 1987-02-12 | — | — | JP | disclosed |
| US-4508806-A | Electrophotographic toner composition | ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-04-02 | — | — | US | disclosed |
| US-3994988-A | CONTAINERS, SEPARATORS, MEDICAL EQUIPMENT | BAXTER LABORATORIES, INC. (US) | 1976-11-30 | — | — | US | disclosed |