Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502107 | 0.92 | SIGMAR1 (0.72) | SIGMAR1SMN1; SMN2CHKAHRH3 | |
| SCHEMBL1043952 | 0.86 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2CHKA | |
| SCHEMBL20804352 | 0.86 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2CHKA | |
| SCHEMBL19285228 | 0.86 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2CHKA | |
| SCHEMBL11158126 | 0.86 | SIGMAR1 (0.64) | SIGMAR1SMN1; SMN2CHKA | |
| SCHEMBL11352512 | 0.84 | SIGMAR1 (0.74) | SIGMAR1HRH3ACHE | |
| SCHEMBL12126812 | 0.83 | CHKA (0.79) | SIGMAR1SMN1; SMN2CHKAHRH3 | |
| SCHEMBL10994325 | 0.83 | HSD17B10 (0.73) | — | |
| SCHEMBL23775600 | 0.82 | SIGMAR1 (0.68) | SIGMAR1SMN1; SMN2CHKAHRH3 | |
| SCHEMBL13256749 | 0.82 | SIGMAR1 (0.68) | SIGMAR1SMN1; SMN2CHKAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234585-A | ANTIALLERGENS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-18 | — | — | US | disclosed |