Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.78 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024563 | 0.80 | CYP19A1 (0.82) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL10965559 | 0.77 | CYP11B1 (0.57) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL10362283 | 0.76 | CYP17A1 (0.77) | CYP19A1CYP17A1CYP26A1 | |
| SCHEMBL11465748 | 0.76 | CYP19A1 (0.59) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL11465917 | 0.76 | CYP19A1 (0.68) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL11567842 | 0.76 | CYP19A1 (0.68) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL10363819 | 0.76 | CYP17A1 (0.76) | CYP19A1CYP17A1CYP26A1 | |
| Lombazole SCHEMBL829388 | 0.75 | CYP17A1 (0.73) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL11481266 | 0.75 | CYP19A1 (0.72) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL11365302 | 0.74 | CYP19A1 (0.71) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238498-A | SKIN DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| EP-0003796-B1 | SUBSTITUTED DIPHENYLMETHYL-IMIDAZOLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
| EP-0003796-A1 | Substituted diphenylmethyl-imidazoles, their preparation and medicaments containing them | BAYER AG (DE) | 1979-09-05 | — | — | EP | disclosed |