Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | CBR1 | P16152 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464870 | 0.87 | FFAR1 (0.54) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 | |
| SCHEMBL8875405 | 0.85 | FFAR1 (0.56) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 | |
| SCHEMBL11463711 | 0.84 | FFAR1 (0.52) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 | |
| SCHEMBL9048125 | 0.83 | FFAR1 (0.51) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 | |
| SCHEMBL11464824 | 0.83 | FFAR1 (0.51) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 | |
| SCHEMBL9656840 | 0.83 | FFAR1 (0.56) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 | |
| SCHEMBL11462409 | 0.82 | FFAR1 (0.50) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 | |
| SCHEMBL9869868 | 0.81 | FFAR1 (0.73) | FFAR1SMN1; SMN2TTRMRGPRX4 | |
| SCHEMBL10900497 | 0.81 | SIGMAR1 (0.47) | SLC6A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11475743 | 0.80 | FFAR1 (0.48) | FFAR1SMN1; SMN2SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4231787-A | 4-(TRIFLUOROMETHYLPHENOXY)PHENOXY-PROPANOLS OR ESTERS | ISHIHARA SANGYO KAISHA LTD. (JP) | 1980-11-04 | — | — | US | disclosed |
| US-4105435-A | 4-(3,5-DIHALO- OR 5-HALOPYRIDYL-2-OXY)PHENOXY PROPANES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1978-08-08 | — | — | US | disclosed |