⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076603 | 0.71 | — | — | |
| SCHEMBL8511284 | 0.69 | — | — | |
| SCHEMBL1960310 | 0.62 | — | — | |
| SCHEMBL4548057 | 0.62 | — | — | |
| SCHEMBL29587059 | 0.62 | — | — | |
| SCHEMBL1416539 | 0.62 | — | — | |
| SCHEMBL268403 | 0.59 | — | — | |
| SCHEMBL20384146 | 0.59 | — | — | |
| SCHEMBL10028832 | 0.59 | — | — | |
| SCHEMBL19457042 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971690-B1 | TRANSLATIONAL DYSFUNCTION BASED THERAPEUTICS | TRANSLATIONAL THERAPEUTICS INC (US) | 2018-10-17 | — | — | EP | claimed |
| EP-0928290-B9 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS INC (US) | 2005-11-09 | — | — | EP | claimed |
| EP-0928290-B1 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS INC (US) | 2005-03-30 | — | — | EP | claimed |
| CN-114981430-A | Nucleic acid for inhibiting C3 expression in cells | 赛伦斯治疗有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114375336-A | Nucleic acids for inhibiting expression of PROS1 in a cell | 伯尔尼大学 | 2022-04-19 | — | — | CN | disclosed |
| WO-2021149329-A1 | NOVEL USE OF HIC-5 INHIBITOR | 学校法人昭和大学 | 2021-07-29 | — | — | WO | disclosed |
| CN-113164589-A | Compositions and methods for modulating monocyte and macrophage inflammatory phenotype and immunotherapy uses thereof | 维西欧制药公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020196736-A1 | RNAI MOLECULE | 日東電工株式会社 | 2020-10-01 | — | — | WO | disclosed |
| WO-2017031918-A1 | LONG-ACTING DIPEPTIDYL PEPTIDASE-IV INHIBITOR, APPLICATIONS, AND PREPARATION METHOD FOR INTERMEDIATE THEREOF | 四川科伦药物研究院有限公司 | 2017-03-02 | — | — | WO | disclosed |
| US-9580420-B2 | Process for the preparation of 4-(8-(2-chlorophenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)bicyclo[2.2.1]heptan-1-ol and novel intermediates therefor | BRISTOL-MEYERS SQUIBB COMPANY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160039813-A1 | PROCESS FOR THE PREPARATION OF 4-(8-(2-CHLOROPHENOXY)-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YL)BICYCLO[2.2.1]HEPTAN-1-OL AND NOVEL INTERMEDIATES THEREFOR | BRISTOL-MYERS SQUIBB COMPANY | 2016-02-11 | — | — | US | disclosed |
| US-8216353-B2 | Photoinitiator is a benzyl ketal compound incorporating a pendent water-soluble group via an oxygen atom or a sulfur atom; exhibits a high photocuring sensitivity, specifically even to black ink, and is easily handled | KONICA MINOLTA HOLDINGS, INC. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-8183259-B2 | Heterocyclic compounds and their uses | AMGEN INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20120095214-A1 | QUINAZOLINONE LINKED PYRROLO[2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-04-19 | — | — | US | disclosed |
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20110275653-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110201600-A1 | CHALCONE LINKED PYRROLO[2,1-C][1, 4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860)) (IN) | 2011-08-18 | — | — | US | disclosed |
| US-20080241424-A1 | Ink-jet ink and ink-jet recording method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-7220765-B2 | Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (SCRAS) (FR) | 2007-05-22 | — | — | US | disclosed |