Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.64 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.64 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | TDP2 | O95551 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510973 | 0.88 | P2RY11 (0.76) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL11466125 | 0.88 | P2RY11 (0.67) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL11411036 | 0.87 | TIMP3 (0.47) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL11481697 | 0.87 | HPSE (0.64) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL11467218 | 0.86 | P2RY11 (0.70) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL17903265 | 0.86 | P2RY11 (0.78) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL11406508 | 0.86 | P2RY11 (0.72) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL5501853 | 0.85 | P2RY11 (0.77) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL11511518 | 0.85 | P2RY11 (0.73) | MEN1KMT2ATIMP3HPSEMAPT | |
| SCHEMBL11476211 | 0.84 | P2RY11 (0.73) | MEN1KMT2ATIMP3HPSEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4180587-A | Ureylene phenylene anionic naphthalenesulfonic acids as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1979-12-25 | — | — | US | disclosed |