Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluquazone SCHEMBL43464 | 0.85 | MAPT (0.58) | MAPTTP53LMNAKCNH2MCHR1 | |
| SCHEMBL11160051 | 0.84 | CASR (0.59) | CASRMAPTTP53LMNA | |
| SCHEMBL11636514 | 0.82 | CASR (0.49) | CASRMAPTTP53LMNAAKR1B10 | |
| SCHEMBL11636311 | 0.80 | CASR (0.53) | CASRMAPTAKR1B10KCNH2 | |
| SCHEMBL11164228 | 0.78 | CASR (0.57) | CASRMAPTTP53LMNA | |
| SCHEMBL11468901 | 0.78 | CASR (0.51) | CASRMAPTTP53LMNA | |
| SCHEMBL11470963 | 0.77 | MAPT (0.57) | MAPTTP53LMNA | |
| SCHEMBL11480424 | 0.77 | MAPT (0.57) | MAPTTP53LMNA | |
| SCHEMBL11468011 | 0.76 | MAPT (0.56) | MAPTTP53LMNA | |
| SCHEMBL11158937 | 0.76 | CASR (0.57) | CASRMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |