Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160051 | 0.91 | CASR (0.59) | CASRTP53LMNAMAPTPTGDR2 | |
| SCHEMBL11459543 | 0.85 | PDE3B (0.47) | CASRTP53LMNAMAPT | |
| SCHEMBL11479043 | 0.85 | NR1I2 (0.59) | PTGER1TP53NR1I2EGFRADRA2A | |
| SCHEMBL11479018 | 0.82 | RXFP1 (0.51) | TP53NR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11158937 | 0.82 | CASR (0.57) | CASRTP53LMNAMAPTPTGDR2 | |
| SCHEMBL11164228 | 0.82 | CASR (0.57) | CASRTP53LMNAMAPT | |
| SCHEMBL11162361 | 0.81 | LMNA (0.54) | TP53LMNAMAPT | |
| SCHEMBL11162244 | 0.81 | CASR (0.50) | CASRPTGER1PDE5ATP53NR1I2 | |
| SCHEMBL11469861 | 0.81 | CASR (0.55) | CASRTP53LMNAMAPTPTGDR2 | |
| SCHEMBL11462576 | 0.80 | CASR (0.59) | CASRTP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |