Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460240 | 0.96 | USP2 (0.41) | USP2GNAI3GNAO1GNAI1SPHK1 | |
| SCHEMBL8032200 | 0.86 | EPHX1 (0.47) | GNAI3GNAO1GNAI1SPHK1EPHX1 | |
| SCHEMBL11501702 | 0.81 | SPHK1 (0.43) | GNAI3GNAO1GNAI1SPHK1EPHX1 | |
| SCHEMBL3070903 | 0.80 | EPHX1 (0.40) | SPHK1EPHX1 | |
| SCHEMBL11459630 | 0.80 | USP2 (0.45) | USP2KDM4EFPR3FPR2SMN1; SMN2 | |
| SCHEMBL11468029 | 0.79 | USP2 (0.36) | USP2GNAI3GNAO1GNAI1SMN1; SMN2 | |
| SCHEMBL11573567 | 0.75 | USP2 (0.37) | USP2GNAI3GNAO1GNAI1TP53 | |
| SCHEMBL13868080 | 0.74 | EPHX1 (0.57) | EPHX1 | |
| SCHEMBL20623094 | 0.74 | EPHX1 (0.57) | EPHX1 | |
| SCHEMBL13097658 | 0.74 | EPHX1 (0.57) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209624-A | Process for preparing substituted bis(amidinoureas) | COOPER LABORATORIES, INC. (US) | 1980-06-24 | — | — | US | claimed |