Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032200 | 0.91 | EPHX1 (0.47) | SPHK1EPHX1EPHX2RRM1CASP2 | |
| SCHEMBL3070903 | 0.85 | EPHX1 (0.40) | SPHK1EPHX1DNM1DPP7 | |
| SCHEMBL11468016 | 0.81 | USP2 (0.44) | SPHK1EPHX1RRM1GNAI3GNAO1 | |
| SCHEMBL11501585 | 0.80 | MLYCD (0.34) | EPHX1RRM1DPP7GNAI3GNAO1 | |
| SCHEMBL11460240 | 0.78 | USP2 (0.41) | SPHK1EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL13868080 | 0.78 | EPHX1 (0.57) | EPHX1EPHX2DNM1CASP2 | |
| SCHEMBL20623094 | 0.78 | EPHX1 (0.57) | EPHX1EPHX2DNM1CASP2 | |
| SCHEMBL13097658 | 0.78 | EPHX1 (0.57) | EPHX1EPHX2DNM1CASP2 | |
| SCHEMBL18047858 | 0.74 | EPHX1 (0.48) | EPHX1EPHX2DNM1CASP2 | |
| SCHEMBL11502077 | 0.74 | ALDH1A1 (0.33) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |