Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735684 | 0.93 | ELANE (0.51) | ELANEMEN1KMT2APTGS1FAAH | |
| SCHEMBL10735683 | 0.93 | ELANE (0.51) | ELANEMEN1KMT2APTGS1FAAH | |
| SCHEMBL10733264 | 0.83 | ELANE (0.48) | ELANEMEN1KMT2APTGS1KDM4E | |
| SCHEMBL10402234 | 0.83 | ELANE (0.48) | ELANEMEN1KMT2APTGS1KDM4E | |
| SCHEMBL10402233 | 0.83 | ELANE (0.48) | ELANEMEN1KMT2APTGS1KDM4E | |
| SCHEMBL9595995 | 0.82 | MEN1 (0.41) | ELANEMEN1KMT2APTGS1FAAH | |
| SCHEMBL10739549 | 0.81 | ELANE (0.50) | ELANEMEN1KMT2APTGS1KDM4E | |
| SCHEMBL10590331 | 0.81 | ELANE (0.46) | ELANEMEN1KMT2APTGS1KDM4E | |
| SCHEMBL10733750 | 0.80 | ELANE (0.55) | ELANEMEN1KMT2APTGS1KDM4E | |
| SCHEMBL21667397 | 0.80 | ELANE (0.57) | ELANEMEN1KMT2APTGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013662-A1 | 2-Penem compounds, a method for their preparation and pharmaceutical compositions comprising them | SCHERING CORPORATION (US) | 1980-07-23 | — | — | EP | disclosed |