Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 9/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525141 | 0.84 | CASP1 (0.34) | MEN1KMT2APTGS1ELANECASP1 | |
| SCHEMBL9596958 | 0.84 | ELANE (0.44) | MEN1KMT2APTGS1ELANE | |
| SCHEMBL11468253 | 0.82 | ELANE (0.47) | MEN1KMT2APTGS1ELANECASP1 | |
| SCHEMBL10694393 | 0.81 | ELANE (0.40) | ELANECASP1FAAH | |
| SCHEMBL10788570 | 0.79 | MEN1 (0.50) | MEN1KMT2APTGS1ELANEKDM4E | |
| SCHEMBL10793112 | 0.79 | MEN1 (0.50) | MEN1KMT2APTGS1ELANEKDM4E | |
| SCHEMBL10792684 | 0.78 | MEN1 (0.46) | MEN1KMT2APTGS1ELANEKDM4E | |
| SCHEMBL10991951 | 0.77 | ELANE (0.39) | MEN1KMT2APTGS1ELANECASP1 | |
| SCHEMBL10791506 | 0.77 | MEN1 (0.48) | MEN1KMT2APTGS1ELANEKDM4E | |
| SCHEMBL9595347 | 0.77 | CASP1 (0.38) | MEN1KMT2AELANECASP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215997-A | Synthesis of beta-lactam compounds | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5153315-A | Penicilllin deriviatives | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4962196-A | (3S, 4R)-3,4-trans-disubstituted azetidin-2-one intermediates | CIBA-GEIGY CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |