Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451308 | 0.91 | ADRB2 (0.55) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10662466 | 0.82 | ADRB2 (0.58) | ADRB2ADRB1ADRB3 | |
| SCHEMBL11451001 | 0.81 | ADRB2 (0.66) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10661301 | 0.80 | ADRB2 (0.57) | ADRB2ADRB1 | |
| SCHEMBL9763132 | 0.80 | ADRB2 (0.70) | ADRB2ADRB1ADRB3 | |
| SCHEMBL14220132 | 0.76 | ADRB2 (0.78) | ADRB2ADRB1 | |
| SCHEMBL9811975 | 0.75 | ADRB2 (0.80) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9811981 | 0.75 | ADRB2 (0.80) | ADRB2ADRB1ADRB3 | |
| SCHEMBL11369787 | 0.75 | ADRB2 (0.52) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13662070 | 0.74 | ADRB2 (0.84) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006735-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | claimed |