Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346358 | 0.78 | DHODH (0.54) | HSD17B10DHODHHPGDPOLBRAB9A | |
| SCHEMBL11634051 | 0.76 | HSD17B10 (0.64) | HSD17B10MAPK1HPGDRAB9ATDP1 | |
| SCHEMBL9562844 | 0.76 | DHODH (0.55) | HSD17B10DHODHHPGDPOLBRAB9A | |
| SCHEMBL8762690 | 0.74 | DHODH (0.76) | DHODHHPGDPOLBPARP1PARP15 | |
| SCHEMBL3915670 | 0.74 | DHODH (0.81) | DHODHPOLBRAB9APARP1PARP15 | |
| SCHEMBL4257455 | 0.73 | MAPK1 (0.68) | HSD17B10MAPK1HPGDPOLBRAB9A | |
| SCHEMBL21874 | 0.73 | MAPK1 (0.56) | HSD17B10MAPK1DHODHHPGDPOLB | |
| SCHEMBL27536466 | 0.71 | PARP1 (0.60) | HSD17B10DHODHHPGDPOLBRAB9A | |
| SCHEMBL7019511 | 0.69 | HSD17B10 (0.58) | HSD17B10MAPK1DHODHHPGDPOLB | |
| SCHEMBL3915266 | 0.69 | DHODH (0.77) | DHODHPOLBRAB9APARP1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201715-A | Process for the anilidization of carboxylic acid esters | WACKER-CHEMIE GMBH (DE) | 1980-05-06 | — | — | US | disclosed |
| EP-0003105-A1 | Process for the anilidation of carboxylic acid esters | Wacker-Chemie GmbH (DE) | 1979-07-25 | — | — | EP | disclosed |