Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762690 | 0.84 | DHODH (0.76) | DHODHPOLBHPGDPARP1PARP15 | |
| SCHEMBL27536466 | 0.81 | PARP1 (0.60) | DHODHTP53MEN1KMT2AHTT | |
| SCHEMBL11346358 | 0.81 | DHODH (0.54) | DHODHMEN1KMT2APOLBHPGD | |
| SCHEMBL3915670 | 0.80 | DHODH (0.81) | DHODHTP53MEN1KMT2AHTT | |
| SCHEMBL11468503 | 0.76 | HSD17B10 (0.49) | DHODHMEN1KMT2APOLBLMNA | |
| SCHEMBL3915266 | 0.75 | DHODH (0.77) | DHODHMEN1KMT2APOLBPARP1 | |
| SCHEMBL20512531 | 0.72 | TP53 (0.56) | TP53MEN1KMT2AHTTKDM4E | |
| SCHEMBL21874 | 0.72 | MAPK1 (0.56) | DHODHMEN1KMT2APOLBHPGD | |
| SCHEMBL249112 | 0.71 | DHODH (1.00) | DHODHPARP1PARP15PARP10PTPN1 | |
| SCHEMBL6692379 | 0.70 | HDAC2 (0.58) | TP53MEN1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005037-A1 | OXETANE AND THIAETANE DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-18 | — | — | WO | claimed |
| EP-0530642-A1 | Herbicidal oxetane and thiaetane derivatives | CIBA-GEIGY AG (CH) | 1993-03-10 | — | — | EP | claimed |
| WO-1993005037-A1 | OXETANE AND THIAETANE DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-18 | — | — | WO | disclosed |
| EP-0530642-A1 | Herbicidal oxetane and thiaetane derivatives | CIBA-GEIGY AG (CH) | 1993-03-10 | — | — | EP | disclosed |