Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463317 | 0.88 | TRPV1 (0.59) | MAPTRXFP1SMN1; SMN2FFAR1LMNA | |
| SCHEMBL11934944 | 0.87 | FFAR1 (0.55) | MAPTRXFP1HDAC1HDAC3MAPK1 | |
| SCHEMBL11229424 | 0.87 | S1PR1 (0.62) | HDAC1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11239458 | 0.87 | S1PR1 (0.62) | HDAC1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11247581 | 0.87 | S1PR1 (0.62) | HDAC1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11461308 | 0.86 | MAPT (0.54) | MAPTRXFP1HDAC1HDAC3MAPK1 | |
| SCHEMBL11248573 | 0.84 | FFAR1 (0.86) | MAPTRXFP1HDAC1HDAC3MAPK1 | |
| SCHEMBL11255743 | 0.84 | FFAR1 (0.52) | MAPTRXFP1HDAC1HDAC3MAPK1 | |
| Oxalic Acid SCHEMBL9374016 | 0.84 | TRPV1 (0.57) | MAPTRXFP1HDAC1HDAC2TRPV1 | |
| SCHEMBL11266761 | 0.83 | HDAC1 (0.54) | MAPTRXFP1HDAC1TRPV1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211783-A | Hypolipidemic and antiatherosclerotic novel 4-(aralkyl- and heteroarylalkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |