Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.86 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.82 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.68 |
| ▸ | GNA15 | P30679 | 1/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596544 | 0.90 | FFAR1 (1.00) | FFAR1FFAR4GNA15PTGER3TDP1 | |
| SCHEMBL11468595 | 0.84 | MAPT (0.65) | FFAR1FFAR4HDAC3MAPK1ADRA1A | |
| SCHEMBL14088994 | 0.84 | FFAR1 (0.67) | FFAR1FFAR4HDAC3MAPK1ADRA1A | |
| Phenylbutanoic Acid SCHEMBL1021513 | 0.82 | HDAC1 (1.00) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| Phenylbutanoic Acid SCHEMBL21219015 | 0.82 | HDAC1 (1.00) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| Phenylbutanoic Acid SCHEMBL1716 | 0.82 | HDAC1 (1.00) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL7636110 | 0.81 | TRPV1 (0.77) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| Phenylbutanoic Acid SCHEMBL726614 | 0.80 | HDAC1 (0.95) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| Phenylbutanoic Acid SCHEMBL2010634 | 0.80 | HDAC1 (0.95) | FFAR1HDAC3MAPK1ADRA1AHDAC4 | |
| Phenylbutanoic Acid SCHEMBL31228551 | 0.80 | HDAC1 (0.95) | FFAR1HDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |