Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756841 | 0.88 | PTGS1 (0.71) | PTGS1AKR1C3AKR1C2NR1H4KDM4E | |
| SCHEMBL28150711 | 0.85 | GRIN2D (0.56) | PTGS1AKR1C3AKR1C2GRIN2DGRIN2A | |
| SCHEMBL11462163 | 0.85 | PTGS1 (0.60) | PTGS1AKR1C3AKR1C2GRIN2DGRIN2A | |
| SCHEMBL12267750 | 0.84 | GRIN2D (0.58) | GRIN2DGRIN2AGRIN2BGRIN2CNR1H4 | |
| Hydrochloric Acid SCHEMBL9400435 | 0.84 | PTGS1 (0.58) | PTGS1AKR1C3AKR1C2GRIN2DGRIN2A | |
| SCHEMBL6551318 | 0.82 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CNR1H4 | |
| SCHEMBL31428506 | 0.82 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CNR1H4 | |
| SCHEMBL4206339 | 0.81 | GRIN2D (0.60) | GRIN2DGRIN2AGRIN2BGRIN2CTBXAS1 | |
| SCHEMBL21617912 | 0.81 | PTGS1 (0.63) | PTGS1AKR1C3AKR1C2NR1H4KDM4E | |
| SCHEMBL11459316 | 0.81 | PTGS1 (0.64) | PTGS1AKR1C3AKR1C2NR1H4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1007063-B | COPOLYESTER | VENO FINE CHEMICAL IND LTD (JP) | 1990-03-07 | — | — | CN | disclosed |
| US-4207241-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTIPRURITIC AGENTS | SYNTEX CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4097674-A | ANTIINFLAMMATORY, ANTIPYRETIC, ANTIPRURITIC AGENTS, ANALGESICS | SYNTEX CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4001301-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTI-PRURITIC | SYNTEX CORPORATION (PM) | 1977-01-04 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3980699-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-09-14 | — | — | US | disclosed |
| US-3978116-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |