SCHEMBL756841

SCHEMBL756841

O=C(O)Cc1ccc2cc(CC(=O)O)ccc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.71
AKR1C3 P42330 1/20 0.71
AKR1C2 P52895 1/20 0.71
GAA P10253 4/20 0.61
KDM4E B2RXH2 4/20 0.61
HPGD P15428 4/20 0.61
HSD17B10 Q99714 4/20 0.61
TSHR P16473 4/20 0.61
MAPT P10636 3/20 0.61
LMNA P02545 2/20 0.61
NFKB1 P19838 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
RGS12 O14924 1/20 0.61
POLB P06746 1/20 0.61
APEX1 P27695 1/20 0.61
THPO P40225 1/20 0.61
BLM P54132 1/20 0.61
GNAI1 P63096 1/20 0.61
PMP22 Q01453 1/20 0.61
HIF1A Q16665 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21617912 0.93 PTGS1 (0.63) PTGS1AKR1C3AKR1C2GAAKDM4E
2-Naphthylacetic Acid SCHEMBL238445 0.91 NR1H4 (0.71) PTGS1AKR1C3AKR1C2GAAKDM4E
SCHEMBL21585550 0.91 PTGS1 (0.62) PTGS1AKR1C3AKR1C2GAAKDM4E
2-Naphthylacetic Acid SCHEMBL30493868 0.91 NR1H4 (0.71) PTGS1AKR1C3AKR1C2GAAKDM4E
2-Naphthylacetic Acid SCHEMBL29366514 0.91 NR1H4 (0.71) PTGS1AKR1C3AKR1C2GAAKDM4E
2-Naphthylacetic Acid SCHEMBL28641469 0.91 NR1H4 (0.71) PTGS1AKR1C3AKR1C2GAAKDM4E
SCHEMBL8813563 0.89 CA2 (0.63) PTGS1AKR1C3AKR1C2GAAKDM4E
2-Naphthylacetic Acid SCHEMBL11437704 0.89 NR1H4 (0.69) PTGS1AKR1C3AKR1C2GAAKDM4E
SCHEMBL31443016 0.89 CA2 (0.63) PTGS1AKR1C3AKR1C2GAAKDM4E
2-Naphthylacetic Acid SCHEMBL10453180 0.89 NR1H4 (0.69) PTGS1AKR1C3AKR1C2GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813473-A Prepolymer, preparation method, michael addition coating with root inhibition effect and waterproof coating 佛山市科顺建筑材料有限公司 2023-09-29 CN claimed
CN-116813473-B Prepolymer, preparation method, michael addition coating with root inhibition effect and waterproof coating 佛山市科顺建筑材料有限公司 2023-12-08 CN disclosed
CN-116813473-A Prepolymer, preparation method, michael addition coating with root inhibition effect and waterproof coating 佛山市科顺建筑材料有限公司 2023-09-29 CN disclosed
CN-116695272-A Breathable cationic dyeable polyester fiber and preparation method thereof 江苏恒科新材料有限公司 2023-09-05 CN disclosed
EP-4234537-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, COMPOUND, AND METHOD FOR MEASURING SKIN SENSITIZATION FUJIFILM Corporation (JP) 2023-08-30 EP disclosed
US-20230258569-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, COMPOUND, AND METHOD FOR MEASURING SKIN SENSITIZATION FUJIFILM CORPORATION (JP) 2023-08-17 US disclosed
CN-113583221-B Preparation method of ultraviolet-resistant damp-heat aging-resistant copolyester 浙江凯普奇新材料科技有限公司 2023-08-01 CN disclosed
CN-113583221-A Preparation method of ultraviolet-resistant wet-heat-aging-resistant copolyester 万凯新材料股份有限公司 2021-11-02 CN disclosed
US-10799496-B2 Naphthylenyl compounds for long-acting injectable compositions and related methods ALKERMES PHARMA IRELAND LIMITED (IE) 2020-10-13 US disclosed
US-10799496-B2 Naphthylenyl compounds for long-acting injectable compositions and related methods ALKERMES PHARMA IRELAND LIMITED (IE) 2020-10-13 US disclosed
US-6632916-B2 Conductive polymer having a phenylene vinylene backbone with a condensed hydrocarbon ring system introduced into the backbone to form a bend in a linear structure of the phenylene vinylene backbone. TOYODA GOSEI CO., LTD. (JP) 2003-10-14 US disclosed
US-6627280-B1 Coated hollow polyester molding, method of reclaiming the same, and solution for surface coating TEIJIN LIMITED (JP) 2003-09-30 US disclosed
US-20030092878-A1 Composite type conductive polymer and process of producing aromatic compound TOYODA GOSEI CO., LTD. (JP) 2003-05-15 US disclosed
US-6511747-B1 High tenacity and dimensionally stabile treated cord; reinforcement material of rubber products such as tires and belts. HYOSUNG CORPORATION (KR) 2003-01-28 US disclosed
EP-1267359-A2 Composite type electroconductive polymer and process of producing an aromatic compound Toyoda Gosei Co., Ltd. (JP) 2002-12-18 EP disclosed
EP-1153963-A1 COATED HOLLOW POLYESTER MOLDING, METHOD OF RECLAIMING THE SAME, AND SOLUTION FOR SURFACE COATING TEIJIN LIMITED (JP) 2001-11-14 EP disclosed
JP-2000015694-A FILM FOR DOOR OF COOKING EQUIPMENT TEIJIN LTD 2000-01-18 JP disclosed
US-5998001-A PHOTOGRAPHIC COMPONENT LAYERS INCLUDING A SILVER HALIDE EMULSION LAYER, WHEREIN A CONTACT ANGLE BETWEEN WATER AND A SURFACE OF THE SIDE HAVING THE MAGNETIC RECORDING LAYER IS FROM 85-100 DEGREES KONICA CORPORATION (JP) 1999-12-07 US disclosed
US-5049295-A Mechanical properties, heat resistance KAWASAKI STEEL CORPORATION (JP) 1991-09-17 US disclosed
EP-0376323-A2 Aromatic polyester, aromatic polyester amide, filaments thereof and compositions thereof each containing an inorganic filler or magnetic powder KAWASAKI STEEL CORPORATION (JP) 1990-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092878-A1 Composite type conductive polymer and process of producing aromatic compound KCNH1, PIEZO1, KCNH3 PTGS1 3927/4885AKR1C3 2354/4885AKR1C2 2827/4885
US-10799496-B2 Naphthylenyl compounds for long-acting injectable compositions and related methods OPRL1, OPRK1, OPRM1 PTGS1 1047/4885AKR1C3 534/4885AKR1C2 505/4885
US-20230258569-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, COMPOUND, AND METHOD FOR MEASURING SKIN SENSITIZATION TST, CUTA, HNMT PTGS1 235/4885AKR1C3 802/4885AKR1C2 880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.