Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565391 | 0.98 | CNR1 (0.50) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL249159 | 0.91 | GAA (0.55) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL7243005 | 0.89 | GAA (0.54) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL1681770 | 0.89 | GAA (0.54) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL1856050 | 0.89 | GAA (0.54) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL3914501 | 0.89 | GAA (0.54) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL3267630 | 0.86 | GAA (0.60) | HTTALDH1A1HPGDSMN1; SMN2CNR1 | |
| SCHEMBL4947216 | 0.85 | ALDH1A1 (0.71) | HTTALDH1A1HPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL7830929 | 0.83 | ALDH1A1 (0.69) | HTTALDH1A1HPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL3432906 | 0.83 | ALDH1A1 (0.69) | HTTALDH1A1HPGDSMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187230-A | Preparation of 5-aroyl-pyrrole compounds | ETHYL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |