Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468753 | 0.92 | EPHX2 (0.65) | EPHX2L3MBTL1CA1CA2CA9 | |
| SCHEMBL9885410 | 0.84 | POLB (0.75) | EPHX2L3MBTL1CYP3A4HTTKMT2A | |
| SCHEMBL10846755 | 0.81 | EPHX2 (0.69) | EPHX2L3MBTL1CA1CA2CA9 | |
| SCHEMBL11460203 | 0.81 | EPHX2 (0.64) | EPHX2CA1CA2CA9KMT2A | |
| SCHEMBL11532514 | 0.81 | EPHX2 (0.60) | EPHX2CYP3A4ALDH1A1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL11458330 | 0.80 | EPHX2 (0.62) | EPHX2CA1CA2CA9KMT2A | |
| SCHEMBL11533149 | 0.79 | EPHX2 (0.60) | EPHX2ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL11530025 | 0.78 | KMT2A (0.82) | EPHX2HTTALDH1A1KMT2APOLB | |
| SCHEMBL11530415 | 0.78 | NPSR1 (0.58) | EPHX2ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL28069120 | 0.78 | KDM4E (0.59) | EPHX2L3MBTL1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183927-A | Substituted phenylthioalkylamines and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1980-01-15 | — | — | US | disclosed |
| US-4155907-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4141983-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4134996-A | METHOD FOR INHIBITING ADP-INDUCED PLATELET AGGREGATION USING PHENYLTHIOALKYLAMINES | THE DOW CHEMICAL COMPANY (US) | 1979-01-16 | — | — | US | disclosed |