Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468956 | 0.92 | EPHX2 (0.77) | EPHX2L3MBTL1KMT2AMEN1CA1 | |
| SCHEMBL10846755 | 0.84 | EPHX2 (0.69) | EPHX2L3MBTL1KMT2ACA1CA2 | |
| SCHEMBL9885410 | 0.82 | POLB (0.75) | EPHX2L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL11468670 | 0.81 | MEN1 (0.60) | EPHX2KMT2AMEN1CA1CA2 | |
| SCHEMBL11531653 | 0.80 | MEN1 (0.72) | EPHX2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL2920100 | 0.80 | MEN1 (0.72) | EPHX2KMT2AMEN1CA1CA2 | |
| SCHEMBL11526865 | 0.80 | KMT2A (0.63) | EPHX2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28069120 | 0.80 | KDM4E (0.59) | EPHX2L3MBTL1KMT2AALDH1A1MAPT | |
| SCHEMBL23747762 | 0.79 | CNR1 (0.62) | EPHX2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL11534382 | 0.78 | MEN1 (0.65) | EPHX2L3MBTL1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183927-A | Substituted phenylthioalkylamines and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1980-01-15 | — | — | US | disclosed |
| US-4155907-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4141983-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4134996-A | METHOD FOR INHIBITING ADP-INDUCED PLATELET AGGREGATION USING PHENYLTHIOALKYLAMINES | THE DOW CHEMICAL COMPANY (US) | 1979-01-16 | — | — | US | disclosed |