Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464531 | 0.86 | CYP3A4 (0.55) | L3MBTL1MEN1KMT2ACYP3A4HDAC1 | |
| SCHEMBL11463533 | 0.86 | TSHR (0.59) | L3MBTL1MEN1KMT2ACYP3A4HDAC1 | |
| SCHEMBL11471634 | 0.86 | MEN1 (0.70) | L3MBTL1MEN1KMT2ACYP3A4HDAC1 | |
| SCHEMBL11472614 | 0.86 | KMT2A (0.60) | L3MBTL1MEN1KMT2ACYP3A4HDAC1 | |
| SCHEMBL11472439 | 0.83 | KMT2A (0.63) | L3MBTL1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL11480901 | 0.83 | PTGS1 (0.60) | L3MBTL1MEN1KMT2ALMNATSHR | |
| SCHEMBL11537220 | 0.82 | MEN1 (0.76) | L3MBTL1MEN1KMT2ACYP3A4IDO1 | |
| SCHEMBL11464516 | 0.82 | MAPT (0.62) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL11480861 | 0.81 | MEN1 (0.57) | L3MBTL1MEN1KMT2ACYP3A4HDAC1 | |
| SCHEMBL11464771 | 0.80 | CYP3A4 (0.56) | L3MBTL1MEN1KMT2ACYP3A4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4236015-A | ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS, FUNGICIDES | WESTWOOD PHARMACEUTICALS, INC. (US) | 1980-11-25 | — | — | US | claimed |