Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | IDH2 | P48735 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538807 | 0.88 | KMT2A (0.67) | MEN1KMT2AIDH2L3MBTL1CYP3A4 | |
| SCHEMBL11541657 | 0.86 | MEN1 (0.76) | MEN1KMT2AIDH2CYP3A4BTK | |
| SCHEMBL11538930 | 0.86 | MEN1 (0.76) | MEN1KMT2AIDH2CYP3A4BTK | |
| SCHEMBL11536552 | 0.86 | KMT2A (1.00) | MEN1KMT2AIDH2L3MBTL1CYP3A4 | |
| SCHEMBL11472293 | 0.83 | MEN1 (0.71) | MEN1KMT2AIDH2CYP3A4BTK | |
| SCHEMBL11537785 | 0.83 | MEN1 (0.71) | MEN1KMT2APTGER3TRPV1 | |
| SCHEMBL11535043 | 0.83 | IDH2 (0.72) | MEN1KMT2AIDH2TRPV1KDR | |
| SCHEMBL11538530 | 0.83 | MEN1 (0.71) | MEN1KMT2AIDH2CYP3A4BTK | |
| SCHEMBL11541067 | 0.83 | MEN1 (0.63) | MEN1KMT2AIDH2L3MBTL1CYP3A4 | |
| SCHEMBL11469185 | 0.82 | L3MBTL1 (0.68) | MEN1KMT2AL3MBTL1CYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160097-A | INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES | WESTWIND PHARMACEUTICALS, INC. (US) | 1979-07-03 | — | — | US | claimed |