SCHEMBL1146945

SCHEMBL1146945

Cc1nccn1CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11250773 0.82
Bromide SCHEMBL18444828 0.80 ALDH1A1 (0.60)
SCHEMBL4779659 0.80 ALDH1A1 (0.72)
SCHEMBL4772963 0.80 KMT2A (0.59)
SCHEMBL15619179 0.79 KMT2A (0.53)
SCHEMBL486434 0.78
SCHEMBL25009512 0.76 ALDH1A1 (0.80)
SCHEMBL11159270 0.76
SCHEMBL6647390 0.76
SCHEMBL17012174 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118580249-A 5-Hydroxyfurocoumarin compound, preparation method and application thereof in preparing antiallergic medicine 西安交通大学 2024-09-03 CN claimed
CN-118580249-A 5-Hydroxyfurocoumarin compound, preparation method and application thereof in preparing antiallergic medicine 西安交通大学 2024-09-03 CN disclosed
US-20110039888-A1 ASYMMETRIC ALPHA FUNCTIONALIZATION AND ALPHA, ALPHA BISFUNCTIONALIZATION OF ALDEHYDES AND KETONES COLTART DON M 2011-02-17 US disclosed
WO-2009131657-A1 ASYMMETRIC ALPHA FUNCTIONALIZATION AND ALPHA, ALPHA BISFUNCTIONALIZATION OF ALDEHYDES AND KETONES DUKE UNIVERSITY (US) 2009-10-29 WO disclosed