SCHEMBL11469482

SCHEMBL11469482

[NH]C(=O)OCc1ccc(/N=N/c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
PPARA Q07869 1/20 0.49
TRPA1 O75762 1/20 0.47
KMT2A Q03164 4/20 0.47
NPC1 O15118 4/20 0.47
MEN1 O00255 3/20 0.47
PLAU P00749 1/20 0.47
ALDH1A1 P00352 7/20 0.46
MAPT P10636 5/20 0.45
RAB9A P51151 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11469483 1.00 PPARG (0.49) PPARGPPARDPPARATRPA1KMT2A
SCHEMBL1696 0.83 ALDH1A1 (0.63) KMT2AALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL114506 0.83 PLAU (0.50) PPARGPPARDPPARATRPA1KMT2A
SCHEMBL114505 0.83 PLAU (0.50) PPARGPPARDPPARATRPA1KMT2A
SCHEMBL3291946 0.83 ALDH1A1 (0.70) PPARGPPARDPPARATRPA1KMT2A
SCHEMBL3291950 0.83 ALDH1A1 (0.70) PPARGPPARDPPARATRPA1KMT2A
SCHEMBL11479675 0.82 ALDH1A1 (0.49) PPARGPPARDPPARAKMT2ANPC1
SCHEMBL11479667 0.82 ALDH1A1 (0.49) PPARGPPARDPPARAKMT2ANPC1
SCHEMBL6545884 0.79 HCAR2 (0.49) PPARGPPARDPPARATRPA1KMT2A
SCHEMBL6545886 0.79 HCAR2 (0.49) PPARGPPARDPPARATRPA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4196291-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1980-04-01 US disclosed
US-4141978-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-02-27 US disclosed
US-4113867-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-09-12 US disclosed
US-4001411-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US disclosed